384-element spectrochip arrays (Sequenom)
90
Structured Review
Sequenom
384-element spectrochip arrays
384 Element Spectrochip Arrays, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/384+spectrochip+array/384+element+silicon+chip+spectrochip/10__1097_slash_md__0000000000034477-67-8-11
Average 90 stars, based on 1 article reviews
384 Element Spectrochip Arrays, supplied by Sequenom, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/384+spectrochip+array/384+element+silicon+chip+spectrochip/10__1097_slash_md__0000000000034477-67-8-11
Average 90 stars, based on 1 article reviews
384-element spectrochip arrays - by Bioz Stars,
2026-11
90/100 stars
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Amplification:Article Title: A functional polymorphism in the promoter of αA-crystallin increases the risk of nAMD Article Snippet: All DNA samples were sent to the company (BGI, The Beijing Genomics Institute, Beijing) for gene detection. .. More specifically, approximately 30 ng DNA samples were amplified (The primer sequences for 6 SNPs of CRYAA gene are shown in ), and then the PCR products were used for locus-specific single-base extension reactions and the following products were desalted and transferred to a Polymerase Chain Reaction:Article Title: A functional polymorphism in the promoter of αA-crystallin increases the risk of nAMD Article Snippet: All DNA samples were sent to the company (BGI, The Beijing Genomics Institute, Beijing) for gene detection. .. More specifically, approximately 30 ng DNA samples were amplified (The primer sequences for 6 SNPs of CRYAA gene are shown in ), and then the PCR products were used for locus-specific single-base extension reactions and the following products were desalted and transferred to a Mass Spectrometry:Article Title: Marker-evaluated selection in rice: shifts in allele frequency among bulks selected in contrasting agricultural environments identify genomic regions of importance to rice adaptation and breeding. Article Snippet: Conventional methods for quantitative trait locus (QTL) mapping require the selection of particular traits to be measured based on assumptions as to their importance.. We have tested an alternative approach for the location of QTLs—marker-evaluated selection—that makes no prior assumptions as to which traits are important.. The results of phenotype selection were evaluated in the products of modified bulk-population breeding that was replicated across a range of rice ecosystems. other:Article Title: UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo. Article Snippet: Atorvastatin is one of the most frequently used 3-hydroxymethylglutaryl coenzyme A reductase inhibitors (statins).. Statins are comparatively safe to use, and they reduce elevated levels of low-density lipoprotein cholesterol, thereby lowering the risk of developing coronary heart disease.. However, the lipid-lowering effect of statins is inadequate in a percentage of patients; also, these drugs are involved in many drug–drug interactions and can cause hepatic and extrahepatic adverse effects, including hepatotoxicity, myopathy, and, rarely, severe rhabdomyolysis.1–4 Despite recent pharmacogenomic advances, only a few of the factors involved in adverse reactions and response to statins have been identified.5–9 Recently, atorvastatin-treated patients experiencing myopathy were found to have higher plasma concentrations of certain metabolites, including cytochrome P450 (CYP) 3A–formed hydroxymetabolites as well as cyclic lactones.10 In a cellular myotoxicity model, these have been shown to be more cytotoxic than the corresponding acids.11 Most statins are extensively metabolized by CYPs,2 but considerably higher metabolic clearances have been found for the corresponding cyclic δ-lactones in vitro;12 this finding is consistent with the high lactone concentrations found in human plasma.10 Furthermore, given their higher lipophilicity, statin lactones are better substrates for CYP3A4; for this reason, it has been suggested that they constitute the major route to CYP3A4-mediated hydroxylation13 (Supplementary Figure S1 online). |